University of California-Berkeley · BiochemistryVance Lab
Russell E Vance · Berkeley, California
Research Focus
Dr. Russell E. Vance's lab at UC Berkeley focuses on understanding how the bacteria Shigella causes disease. By developing a new mouse model that mimics human infection, the lab investigates the immune response and key cellular players that contribute to disease severity and resolution. Their research has significant implications for public health, particularly in combatting diarrheal diseases that affect millions worldwide.
Shigellapathogenesismouse modelimmune responsemacrophages
Research Aims
3AIM 01Develop a physiological mouse model for studying Shigella infections.
AIM 02Investigate the role of macrophages in resistance to Shigella.
AIM 03Identify cytokine pathways involved in Shigella pathogenesis.
Skills the Lab Values
in vivo experimentationmouse modelsflow cytometrycytokine profilingbacterial culture
Output against the department
Publications196top 43% of dept.172nd of 402
this lab
most publishedleast published
Citations24ktop 16% of dept.64th of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.