Cornell University · Microbiology & ImmunologyRudd Immunology Lab
Brian David Rudd · Ithaca, New York
Research Focus
Dr. Brian David Rudd's lab focuses on understanding how the immune system, particularly T cells, develops and functions from infancy to adulthood. By studying lymph node responses to infections, the lab aims to create a detailed map of T cell activation and location throughout different life stages. This research can lead to better vaccines and immunotherapies that are tailored to enhance immunity, especially in early life.
T cellsimmunitylymph nodesvaccinesimmunotherapyspatial transcriptomicsinfectiondevelopmentinfancymicrobial exposure
Research Aims
4AIM 01Construct a molecular atlas of T cell development in lymph nodes across different life stages.
AIM 02Determine how the spatial organization of T cells changes from infancy to adulthood.
AIM 03Examine the lymph node's influence on CD8+ T cell responses to infections in infants and adults.
AIM 04Evaluate how microbial exposure impacts the development of lymphoid CD8+ T cells.
Skills the Lab Values
cell culturemouse modelsspatial transcriptomicsimmunofluorescenceflow cytometryPCRdata visualizationRNA sequencingmolecular cloning
Output against the department
Publications131top 50% of dept.241st of 486
this lab
most publishedleast published
Citations2.8kbottom 18% of dept.399th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.