University of Washington-Seattle Campus · PharmacologyZweifel Emotion Lab
Larry S Zweifel · Seattle, Washington
Research Focus
Dr. Larry S. Zweifel's lab at the University of Washington focuses on how our emotions, especially positive and negative feelings, interact in the brain to affect learning and memory. By studying the central amygdala, a brain area involved in processing emotions, the lab aims to understand how positive stimuli can alter responses to fear and anxiety. This research has important implications for improving therapies for anxiety disorders, making them more effective in treating patients.
emotional stimulilearningmemoryanxiety disordersamygdaladopaminefear extinctionbehavioral therapyneuroscience
Research Aims
5AIM 01Investigate how positive stimuli impact fear learning and memory.
AIM 02Determine the role of dopamine in fear extinction processes.
AIM 03Explore interaction between positive and negative emotional states during learning.
AIM 04Identify specific neurotransmitter receptors involved in affective state modulation.
AIM 05Assess the implications of emotional interaction for behavioral therapy effectiveness.
Skills the Lab Values
animal handlingelectrophysiologyimmunohistochemistrybehavioral testingdata analysisneuropharmacologycell cultureimaging techniquesmolecular biologyrecording neural activity
Output against the department
Publications179bottom 49% of dept.236th of 462
this lab
most publishedleast published
Citations9.8ktop 39% of dept.179th of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.