University of California-Davis · NeuroscienceDecarli Cognition Lab
Charles Decarli · Davis, California
Research Focus
Dr. Charles Decarli's lab focuses on understanding how white matter lesions in the brain affect cognitive functions, particularly in aging populations. They study the impact of vascular risk factors on Alzheimer's disease and other forms of dementia, emphasizing diverse groups, particularly Latinos and African Americans, who are at increased risk. Through advanced MRI techniques, the lab aims to develop predictive models that can lead to better management and treatment strategies for cognitive impairments in these populations.
Alzheimer's Diseasevascular cognitive impairmentwhite matter lesionsMRILatino health disparitiesagingcognitive declinebrain imagingdementia
Research Aims
3AIM 01Identify the characteristics of white matter injury that influence cognitive performance and health outcomes.
AIM 02Evaluate the mechanisms by which white matter injury progresses and impacts cognition.
AIM 03Develop and validate a predictive risk model for managing patients with white matter lesions and cognitive complaints.
Skills the Lab Values
MRI imagingcognitive assessmentdata analysisclinical evaluationsstatistical modelingbiomarker analysislongitudinal studieshealth informaticsepidemiological research
Output against the department
Publications942top 4% of dept.26th of 671
this lab
most publishedleast published
Citations66ktop 4% of dept.27th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.