Florida International University · BiologyGlycobiology and Melanoma Research Unit
Charles J Dimitroff · Miami, Florida
Research Focus
Dr. Charles J Dimitroff’s lab at Florida International University focuses on understanding how certain sugars on melanoma cells affect the progression of the disease. The team investigates specific proteins called galectins that interact with these sugars, which may help in predicting which melanoma cases will worsen. Ultimately, their research aims to identify new biomarkers to enhance treatment options for patients suffering from metastatic melanoma.
melanomaglycomegalectinbiomarkersmetastasistherapeutic targetsimmune responsecancer treatmentglycobiology
Research Aims
5AIM 01Examine the role of Gal-8 in melanoma progression.
AIM 02Analyze the relationship between Gal-8 and tumor growth.
AIM 03Investigate how the glycome affects therapy resistance in melanoma cells.
AIM 04Determine if Gal-8 can be a biomarker for melanoma metastasis.
AIM 05Assess the impact of Gal-8 on immune responses in melanoma.
Skills the Lab Values
molecular characterizationmouse modelscell cultureglycan analysisprotein binding assaysbioinformaticsclinical tissue analysisflow cytometryWestern blotpreclinical modeling
Output against the department
Publications105bottom 36% of dept.654th of 1,033
this lab
most publishedleast published
Citations3.6kbottom 27% of dept.755th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.