University of Maryland, Baltimore · Biomedical EngineeringLiang Lab
Yajie Liang · Baltimore, Maryland
Research Focus
Dr. Yajie Liang's lab focuses on innovative treatments for chronic stroke using advanced technologies like brain organoids and flexible bioelectronics. The research aims to develop a novel therapy that integrates engineered brain tissues with electrical stimulation to enhance recovery in stroke-affected patients. This groundbreaking approach hopes to improve the quality of life for individuals who suffer from severe motor deficits due to stroke.
brain organoidschronic strokebioelectronicselectrical stimulationmotor functionneural differentiationtissue engineeringtransplantation
Research Aims
5AIM 01Develop flexible bioelectronics for brain organoid integration with adult brains
AIM 02Test the effects of electrical stimulation on brain organoid survival and integration
AIM 03Evaluate the repair potential of microinstrumented organoids in a chronic stroke model
AIM 04Establish a dynamic platform for monitoring stroke recovery in real-time
AIM 05Investigate the therapeutic potential of brain organoids in restoring motor function post-stroke
Skills the Lab Values
3D culture techniqueselectrophysiologymultiphoton imagingviral vector deliverytissue engineeringanimal modelsmicroelectrode designdata visualizationbiostatistics
Output against the department
Publications121bottom 25% of dept.446th of 595
this lab
most publishedleast published
Citations6.1kbottom 46% of dept.321st of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.