Yale University · Biomedical EngineeringTumor DNA Repair and Therapy Unit
Peter M Glazer · New Haven, Connecticut
Research Focus
Dr. Peter Glazer's lab focuses on finding ways to treat cancer by targeting specific weaknesses in tumor DNA repair processes. They study how certain mutations can make tumors more vulnerable to treatments that exploit these weaknesses. The lab combines basic science research with clinical trials to develop innovative therapies, including unique antibody treatments and small molecule drug combinations, aimed at improving outcomes for cancer patients.
DNA repaircancer therapyPARP inhibitorstumor targetingantibody-based therapies
Research Aims
5AIM 01Identify DNA repair deficiencies in cancer cells
AIM 02Develop novel strategies to overcome treatment resistance
AIM 03Create targeted therapies using antibody-drug conjugates
AIM 04Investigate the mechanisms of action for new therapeutic agents
AIM 05Conduct clinical trials for innovative cancer treatments
Skills the Lab Values
CRISPR screeningRNA sequencingtumor modelscell cultureantibody engineering
Output against the department
Publications470top 18% of dept.105th of 595
this lab
most publishedleast published
Citations19ktop 18% of dept.108th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.