University of North Carolina at Chapel Hill · Biomedical EngineeringAdvanced Microscopy and Biophysics Lab
Wesley R. Legant · Chapel Hill, North Carolina
Research Focus
Wesley R. Legant's lab at the University of North Carolina Chapel Hill focuses on developing advanced microscopy techniques to study biological systems at multiple scales. By combining optical innovations and computer vision, the lab aims to create intelligent microscopes that can analyze live samples in real time. Their research investigates how proteins operate within the cell nucleus, enhancing our understanding of fundamental cellular processes.
microscopycell biologyprotein dynamicscomputer visionlight sheet imagingepigeneticsnuclear organizationbiological imagingspatiotemporal analysis
Research Aims
5AIM 01Develop new microscopy technologies that enhance biological observation.
AIM 02Utilize computer vision to analyze and interpret imaging data effectively.
AIM 03Investigate the behavior of proteins within the cell nucleus.
AIM 04Explore the interactions of proteins and chromatin in epigenetic processes.
AIM 05Create autonomous microscopes that can adapt to experimental needs.
Skills the Lab Values
microscopy techniquesdata analysisreal-time imagingcomputer vision softwarelight sheet microscopysingle molecule imagingimage processingimage reconstructioncell culture
Output against the department
Publications98bottom 17% of dept.494th of 595
this lab
most publishedleast published
Citations11ktop 33% of dept.197th of 595
this lab
most citedleast cited
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