University of Minnesota-Twin Cities · PharmacologyMonkeypox Antiviral Development Lab
Zhengqiang Wang · Minneapolis, Minnesota
Research Focus
The lab led by Dr. Zhengqiang Wang at the University of Minnesota focuses on developing new antiviral drugs specifically targeting the monkeypox virus (mpox). The current need for effective treatments arises from a global outbreak and the limitations of existing smallpox medications against this virus. The team employs a multidisciplinary approach, combining various fields to optimize drug candidates and understand their mechanisms of action.
monkeypoxMPXVantiviralsdrug developmentorthopoxviruses
Research Aims
3AIM 01Optimize and expand identified hit compounds for antiviral activity.
AIM 02Conduct in vivo pharmacokinetics and toxicity studies in mouse models.
AIM 03Determine the mechanisms of action of optimized antiviral leads.
Skills the Lab Values
medicinal chemistryvirologyanimal modelsproteomicsADME profiling
Output against the department
Publications102bottom 26% of dept.340th of 462
this lab
most publishedleast published
Citations2.9kbottom 22% of dept.361st of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.