Oakland University · BiologyCell Stress and Recovery Lab
Chhabi K Govind · Rochester Hills, Michigan
Research Focus
Dr. Chhabi K Govind's lab at Oakland University focuses on understanding how cells recover from stress by studying the process of autophagy, which helps cells recycle and degrade components when faced with starvation or other stresses. They use the yeast Saccharomyces cerevisiae as a model organism to explore the role of chromatin structure and specific protein complexes in this recovery process. Their research aims to uncover important mechanisms that maintain cell function and survival during challenging conditions, with implications for health and disease.
autophagychromatin remodelingcell survivalstress responseS. cerevisiaeribophagyhistone modificationsgene expressionproteomics
Research Aims
5AIM 01Characterize changes in chromatin structure and transcription during extended starvation.
AIM 02Determine the role of RSC and FACT complexes in cellular recovery from stress.
AIM 03Examine how depletion of RSC affects ribophagy processes.
AIM 04Identify factors that promote ribophagy in an RSC-dependent manner.
AIM 05Investigate the impact of chromatin factors on cell survival during prolonged stress.
Skills the Lab Values
cell cultureChIP-seqWestern blotgene expression analysismicroscopymolecular cloningyeast geneticsRNA sequencingautophagy assays
Output against the department
Publications39bottom 7% of dept.956th of 1,033
this lab
most publishedleast published
Citations2.1kbottom 15% of dept.879th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.