University of Alabama at Birmingham · NeuroscienceThe Neurogenetics Lab
Craig M Powell · Birmingham, Alabama
Research Focus
Dr. Craig M Powell's lab at the University of Alabama at Birmingham focuses on understanding the genetic causes of neurodevelopmental disorders like autism and intellectual disability. They use mouse models to investigate specific genes and their effects on brain function and behavior. By combining advanced techniques like RNA sequencing and MRI, the lab aims to identify potential therapies for these conditions in the future.
neurodevelopmental disordersautismintellectual disabilitymouse modelsgene expressionbehavioral studieselectrophysiologychromatin modificationsRNA sequencingMRI
Research Aims
5AIM 01Characterize the function of a gene implicated in neurodevelopmental disorders using a mouse model.
AIM 02Analyze gene expression and chromatin modifications during critical developmental periods.
AIM 03Examine morphological changes in the brain using structural MRI.
AIM 04Profile behavioral changes related to learning, memory, and social interactions.
AIM 05Investigate synaptic and neuronal function in specific brain regions.
Skills the Lab Values
RNA sequencingchromatin state analysismouse modelsmagnetic resonance imaging (MRI)electrophysiologybehavioral assaysdata analysisslice electrophysiologymultiome sequencingmorphological analysis
Output against the department
Publications121bottom 42% of dept.387th of 671
this lab
most publishedleast published
Citations9.3ktop 42% of dept.283rd of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.