Stanford University · BiologyEndometrial Cancer Genomics Unit
Brooke E Howitt · Stanford, California
Research Focus
Dr. Brooke Howitt's lab at Stanford University focuses on understanding the complex nature of endometrial cancer, which is the most common cancer affecting the female reproductive system. By using advanced techniques to analyze single cells, the lab aims to uncover how tumors differ at a genetic level and how these differences affect treatment responses. This research will help identify better ways to classify, treat, and predict outcomes for patients with this disease.
endometrial cancersingle cell genomicstumor heterogeneityclonal evolutionpersonalized medicine
Research Aims
3AIM 01Develop bioinformatics tools for single-cell mutation calling.
AIM 02Profile existing endometrial carcinoma cohorts to map clonal trajectories.
AIM 03Investigate the spatial organization of endometrial cancer cells.
Skills the Lab Values
bioinformaticssingle-cell RNA sequencinggenotypingtissue sample processingdata analysisspatial transcriptomicsmolecular profilingcell culturedigital pathology
Output against the department
Publications332top 15% of dept.159th of 1,033
this lab
most publishedleast published
Citations13ktop 28% of dept.294th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.