Northeast Ohio Medical University · BiologyThe Cholinergic Auditory Lab
Brett R Schofield · Rootstown, Ohio
Research Focus
Dr. Brett R. Schofield's lab at Northeast Ohio Medical University investigates how the neurotransmitter acetylcholine influences hearing and auditory processing in the brain. Their research focuses on the complex circuits in the auditory system, particularly how higher brain areas modulate auditory information through cholinergic pathways. By understanding these mechanisms, the lab aims to contribute to developing therapeutic strategies for hearing-related issues.
Acetylcholineauditory processingcircuitrycholinergic pathwaysbrainstemneurotransmitterhearing lossauditory systemtransgenic mice
Research Aims
4AIM 01Identify sources of cholinergic input to brainstem auditory nuclei.
AIM 02Investigate divergent projections from cholinergic cells in the auditory system.
AIM 03Determine cholinergic receptor types associated with specific brainstem circuits.
AIM 04Explore the connections between auditory cortex projections and cholinergic cells.
Skills the Lab Values
viral vector techniquestransgenic mouse modelingmulti-label tracingfluorescent in situ hybridizationanatomical tract tracingdata analysisneuroanatomyauditory system dissectioncircuit mapping
Output against the department
Publications148top 46% of dept.472nd of 1,033
this lab
most publishedleast published
Citations6.0kbottom 44% of dept.581st of 1,033
this lab
most citedleast cited
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