MUMarquette University · Chemistry
Nonheme Iron Chemistry Lab
Adam T Fiedler · Milwaukee, Wisconsin
Research Focus
Dr. Adam T. Fiedler's lab at Marquette University focuses on studying how certain enzymes, particularly those containing nonheme iron, oxidize sulfur-containing compounds. The research aims to uncover the mechanisms behind these reactions through the design of synthetic models that mimic the active sites of these enzymes, which are important for various biological processes, including amino acid metabolism and the production of crucial compounds. Undergraduate students are actively involved in this hands-on research, gaining valuable experience in chemistry techniques.
nonheme iron enzymessulfur oxidationamino acid metabolismsynthetic modelsspectroscopybio-inspired chemistrycatalysisenzyme mechanisms
Research Aims
3AIM 01Develop synthetic models of enzymes like sulfoxide synthases to understand their catalytic activity.
AIM 02Explore oxygen reaction mechanisms using synthetic models of dioxygenases.
AIM 03Characterize the geometric and electronic structures of key enzymes through spectroscopic studies.
Skills the Lab Values
inorganic synthesisspectroscopic techniquescrystallographyenzyme preparationtheoretical methodssynthetic modelingactive-site characterizationreaction mechanism explorationgeometric structure analysis
Output against the department
Publications121bottom 26% of dept.160th of 216
this lab
most publishedleast published
Citations2.0kbottom 16% of dept.182nd of 216
this lab
most citedleast cited
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