The University of Texas at Dallas · BiologyPain Mechanisms Laboratory
Yannick Fotio · Richardson, Texas
Research Focus
Yannick Fotio's lab at the University of Texas Dallas focuses on understanding the biological mechanisms behind chronic pain, a significant health issue affecting millions. The research investigates the role of a specific enzyme, N-Acylethanolamine Acid Amidase (NAAA), in pain signaling and how it may contribute to the transition from acute to chronic pain. By exploring metabolic changes in cells after injury, the lab aims to uncover novel therapeutic targets for managing chronic pain.
chronic painlipid signalingNAAAmetabolic reprogramminghyperalgesic priming
Research Aims
3AIM 01Investigate the receptor systems involved in NAAA-mediated hyperalgesic priming.
AIM 02Identify peripheral cell types that influence NAAA's role in pain mechanisms.
AIM 03Elucidate the molecular mechanisms linking NAAA activity to metabolic shifts in pain pathways.
Skills the Lab Values
cell culturegenetic engineeringpharmacologyflow cytometryimmunohistochemistrytranscriptomicsdata analysisbiochemical assays
Output against the department
Publications40bottom 8% of dept.951st of 1,033
this lab
most publishedleast published
Citations535bottom 2% of dept.1,010th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.