University of California-Los Angeles · PharmacologyStoyanova Cancer Lab
Tanya I Stoyanova · Los Angeles, California
Research Focus
Dr. Tanya Stoyanova's lab at UCLA focuses on discovering new treatments for advanced prostate cancer, particularly forms that are resistant to current therapies. The research aims to better understand the role of a protein called ATAD2, which is overactive in aggressive prostate cancer types, and to test new drugs that inhibit ATAD2 to see if they can help stop cancer growth. This work is essential because advanced prostate cancer has few effective treatment options and significantly affects men's health.
prostate cancerATAD2NEPCandrogen deprivation therapycombination therapy
Research Aims
3AIM 01Test ATAD2 levels in clinical prostate cancer specimens.
AIM 02Investigate how ATAD2 contributes to prostate tumor growth and progression.
AIM 03Evaluate the effectiveness of ATAD2 inhibitors in treating advanced prostate cancer.
Skills the Lab Values
cell culturepatient-derived xenograftsWestern blotChIP-seqin vivo tumor modeling
Output against the department
Publications144bottom 40% of dept.277th of 462
this lab
most publishedleast published
Citations4.3kbottom 33% of dept.311th of 462
this lab
most citedleast cited
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