Canine Oncology and Immunotherapy Unit
Cheryl A London · Medford, Massachusetts
Tufts University · Biology
Research focus
Dr. Cheryl A. London's lab at Tufts University focuses on improving cancer therapies through innovative research involving dogs. The lab works on enhancing the immune response in canine osteosarcoma by activating dendritic cells and also investigates clonal hematopoiesis in dogs to understand its implications for cancer treatment. Through clinical trials and the study of immune responses, the research aims to translate findings from canine models to improve human cancer therapies.
canine oncologydendritic cell activationimmune responseclonal hematopoiesiscancer therapyveterinary clinical researchtranslational medicinebiobankingtumor microenvironment
Research aims
5AIM 01Investigate the role of dendritic cell hyperactivation in generating anti-tumor immunity in dogs with osteosarcoma.
AIM 02Model clonal hematopoiesis in pet dogs to study its effects on cancer treatment.
AIM 03Optimize the integration of veterinary research findings with human health practices.
AIM 04Evaluate the immune landscape of dogs undergoing cancer treatment using biobanked samples.
AIM 05Assess the effectiveness of novel vaccine platforms in enhancing immune responses against cancer.
Skills the lab values
dendritic cell cultureflow cytometryclinical trial designimmune profilingDNA sequencingbiological sample processingimmuno-oncology techniquespreclinical animal modelsstatistical analysisbioinformatics
Output against the department
313publicationstop 17% of the department178th of 1,033
most publishedleast published
12kcitationstop 30% of the department310th of 1,033
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. Position on each rail is this lab's rank, not its distance from the top: a department runs from one paper to tens of thousands, so rank is the only comparison that stays readable across it.