RUThe Rockefeller University · Neuroscience
Rajasethupathy Memory Lab
Priya Rajasethupathy · New York, New York
Research Focus
Dr. Priya Rajasethupathy's lab at Rockefeller University focuses on understanding how the thalamus contributes to working memory, particularly in the context of deficits seen in disorders like ADHD and schizophrenia. The lab's research incorporates both chronic and acute molecular studies to explore the role of a newly identified receptor, Gpr12, in maintaining thalamo-cortical activity that underlies memory function. Ultimately, their work aims to uncover therapeutic targets to improve short-term memory capabilities in affected individuals.
working memorythalamusschizophreniaGpr12short-term memoryADHDneural activitytherapeutic targetscognitive deficits
Research Aims
5AIM 01Identify the chronic transcriptional programs regulated by Gpr12 in the thalamus.
AIM 02Investigate the acute signaling pathways activated during working memory tasks.
AIM 03Link the function of Gpr12 to thalamo-cortical synchrony during memory maintenance.
AIM 04Explore new therapeutic targets for reversing memory deficits in mental health disorders.
AIM 05Understand the impact of thalamus on cognitive processes associated with working memory.
Skills the Lab Values
molecular biology techniquesanimal modelsgene expression analysisimmunohistochemistrybehavioral assaystranscriptional regulationWestern blottingdata analysis in neurosciencecalcium imaging
Output against the department
Publications22bottom 3% of dept.649th of 671
this lab
most publishedleast published
Citations2.4kbottom 15% of dept.570th of 671
this lab
most citedleast cited
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