Michigan State University · PhysiologyRobison Immunology Lab
Alfred J Robison · East Lansing, Michigan
Research Focus
Dr. Alfred J Robison's lab at Michigan State University focuses on understanding how innate immune cells called mast cells function in stress and disease. They investigate the genetic and transcriptional mechanisms that regulate these cells, looking for ways to develop new treatments for conditions like allergies, infections, and mood disorders. The lab also studies how stress affects brain circuits, particularly in men and women, to identify sex-specific factors that contribute to resilience in mood disorders.
mast cellsgene expressionstress resiliencemood disordersneuroimmune mechanismstestosteroneFosBanxietydepressionmental health
Research Aims
3AIM 01Investigate the role of FosB in regulating mast cell activation and function.
AIM 02Characterize behavioral responses to stress using transgenic mouse models lacking FosB in mast cells.
AIM 03Identify gene targets of FosB in mast cells to uncover potential therapeutic targets for immune-related conditions.
Skills the Lab Values
immunohistochemistryin vivo Ca2+ imagingRNA sequencing (RNA-seq)virus-mediated gene deliverymouse modelstransgenic techniquesbehavioral assaysmolecular cloningdata analysismicroscopy
Output against the department
Publications131bottom 42% of dept.164th of 286
this lab
most publishedleast published
Citations8.0ktop 41% of dept.117th of 286
this lab
most citedleast cited
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