University of Southern California · Biomedical EngineeringWang Lab
Yingxiao Wang · Los Angeles, California
Research Focus
Dr. Yingxiao Wang's lab focuses on innovative approaches to cancer treatment and vascular disease. They develop cutting-edge technologies like wireless devices to enhance CAR T cell immunotherapy by activating these immune cells precisely at tumor sites. Additionally, their research integrates single-cell imaging and gene editing techniques to understand how blood flow affects endothelial cell function, aiming to find therapeutic targets for cardiovascular diseases.
CAR T cell therapysolid tumorsimmunotherapysingle-cell imagingvascular diseasesCRISPRepigeneticsultrasoundmechanomedicinebiodegradable devices
Research Aims
5AIM 01Develop a wearable thermal activator for CAR T cell immunotherapy.
AIM 02Investigate how blood flow affects endothelial cell gene expression.
AIM 03Utilize ultrasound to manipulate gene expression non-invasively.
AIM 04Assess the therapeutic efficacy of engineered CAR T cells in vivo.
AIM 05Explore epigenetic mechanisms linked to vascular function.
Skills the Lab Values
molecular cloningcell cultureCRISPR gene editingsingle-cell RNA sequencingimmunoassaysoptogeneticsultrasound technologybiodegradable material fabricationlive cell imagingbioinformatics analysis
Output against the department
Publications317top 29% of dept.174th of 595
this lab
most publishedleast published
Citations9.2ktop 37% of dept.223rd of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.