University of Illinois Urbana-Champaign · BiochemistryThe RiPPs Frontier
Satish K Nair · Champaign, Illinois
Research Focus
Dr. Satish K Nair's lab at the University of Illinois studies natural products called RiPPs, which are created from simple peptide sequences and have various medical applications. The lab focuses on understanding how certain enzymes transform these peptides into active compounds that can fight diseases like cancer and infections. By investigating the structure and function of these enzymes, the research aims to develop new and improved therapeutic drugs.
RiPPsnatural productsenzyme mechanismspeptide synthesistherapeuticsbiochemical engineeringsubstrate recognitionbioactive moleculesantibiotics
Research Aims
5AIM 01Investigate the mechanisms of RiPP biosynthetic enzymes.
AIM 02Explore substrate recognition and tolerance in enzyme function.
AIM 03Develop techniques for producing novel bioactive compounds.
AIM 04Enhance the properties of existing therapeutic peptides.
AIM 05Discover new therapeutic applications for RiPPs.
Skills the Lab Values
biochemical assaysprotein purificationenzyme kineticsstructural biology techniquespeptide synthesisgenetic engineeringbioinformaticsspectroscopymolecular cloning
Output against the department
Publications259top 28% of dept.110th of 402
this lab
most publishedleast published
Citations14ktop 36% of dept.143rd of 402
this lab
most citedleast cited
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