University of Maryland, Baltimore · Microbiology & ImmunologyLipid Dynamics and Neurobiology Lab
Alison J Scott · Baltimore, Maryland
Research Focus
Dr. Alison J. Scott's lab at the University of Maryland Baltimore studies how lipids, a type of fat molecule, impact aging and Alzheimer's disease. Using advanced imaging techniques, the lab examines lipid droplet densities in the brain, aiming to better understand their role in health and disease. This research hopes to improve our understanding of lipid behavior, leading to new insights and potential therapies for age-related brain disorders.
lipid homeostasisAlzheimer's diseaseaginglipidomicsmass spectrometry imagingspatial lipid mappingmachine learningneurobiologydementia
Research Aims
4AIM 01Define lipid droplet homeostasis in the context of aging and Alzheimer's disease.
AIM 02Characterize lipid profiles across different brain regions and their relationship to age and disease.
AIM 03Utilize mass spectrometry imaging to create detailed maps of lipid distributions in brain tissues.
AIM 04Develop lipid fingerprints that correlate with specific aging and Alzheimer's disease phenotypes.
Skills the Lab Values
mass spectrometrylipidomicsimmunohistochemistrycell culturemachine learningdata analysisbrain mappingphenotypic analysisspatial transcriptomics
Output against the department
Publications120bottom 46% of dept.263rd of 486
this lab
most publishedleast published
Citations3.2kbottom 23% of dept.375th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.