Massachusetts Institute of Technology · ChemistryIron Catalyst Lab
Daniel Leif Migdow Suess · Cambridge, Massachusetts
Research Focus
Dr. Daniel Leif Migdow Suess's lab focuses on studying iron-sulfur enzymes, which are important in many biological processes and diseases. The lab aims to uncover the mechanisms of these enzymes by developing synthetic models that resemble their natural forms and by improving the techniques used to analyze them. Through this work, the lab seeks to enhance our understanding of how these enzymes function, which could lead to better disease-targeted therapies.
iron-sulfur enzymessynthetic modelsspectroscopic techniquesmechanistic studiesenzyme inhibitors
Research Aims
5AIM 01Develop synthetic models to study iron-sulfur enzyme intermediates.
AIM 02Enhance spectroscopic techniques for better resolution of enzyme intermediates.
AIM 03Investigate the electronic structures of iron-sulfur clusters.
AIM 04Test hypotheses on enzyme reactivity patterns using synthetic chemistry.
AIM 05Study the implications of Fe-S enzymes in human health and disease.
Skills the Lab Values
synthetic chemistryspectroscopysite-selective labelingenzymatic assaysdata analysis
Output against the department
Publications185bottom 44% of dept.120th of 216
this lab
most publishedleast published
Citations2.0kbottom 16% of dept.181st of 216
this lab
most citedleast cited
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