University of Pittsburgh-Pittsburgh Campus · BiologyCenter for Evolutionary Genomics
Nathaniel L Clark · Pittsburgh, Pennsylvania
Research Focus
Dr. Nathaniel L. Clark's lab focuses on connecting genetic information with specific traits seen in various species. By developing advanced computational tools, the lab studies how genetic changes lead to evolution in features like body size and metabolism. This research has broad implications, including the identification of traits relevant to human health and disease.
computational genomicsphenotypic convergencegene regulationevolutionadaptive traitscomparative genomicsmachine learningphenotype analysis
Research Aims
4AIM 01Develop computational tools to analyze genomic regions linked to traits across species.
AIM 02Identify regulatory regions responsible for the evolution of large body size in mammals and birds.
AIM 03Create methods to distinguish adaptive genetic changes from neutral evolution.
AIM 04Benchmark and enhance the performance of the RERconverge platform for larger datasets.
Skills the Lab Values
bioinformaticsR programmingstatistical analysisgenome annotationmachine learning techniquesdata visualizationcomparative genomicscoding in PythonNext-Generation Sequencing (NGS) analysis
Output against the department
Publications143top 48% of dept.489th of 1,033
this lab
most publishedleast published
Citations3.7kbottom 29% of dept.737th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.