University of California-San Diego · EngineeringZhang Drug Delivery Lab
Liangfang Zhang · La Jolla, California
Research Focus
Dr. Liangfang Zhang's lab at UC San Diego focuses on developing innovative microrobots for targeted drug delivery to treat serious lung infections caused by drug-resistant bacteria. These living microrobots, derived from modified microalgae and nanoparticles, aim to enhance drug effectiveness and minimize side effects by improving how drugs are delivered to infected lung tissues. The research addresses a critical public health issue as it seeks to provide new treatment options for patients suffering from severe pulmonary infections.
microrobotsdrug deliverypulmonary infectionsantimicrobial resistancebiomimetic nanoparticles
Research Aims
3AIM 01Optimize the formulation of algae-NP-robots for better drug delivery.
AIM 02Investigate how algae-NP-robots clear bacterial infections in lung models.
AIM 03Extend the use of algae-NP-robots to treat infections caused by Gram-positive bacteria.
Skills the Lab Values
microalgae manipulationnanoparticle formulationin vitro drug testinganimal models of infectionimmunological assays
Output against the department
Publications388top 18% of dept.51st of 278
this lab
most publishedleast published
Citations57ktop 4% of dept.11th of 278
this lab
most citedleast cited
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