UTHThe University of Texas Health Science Center at Houston · Microbiology & Immunology
Fungal Pathogen Interactions Lab
Michael C Lorenz · Houston, Texas
Research Focus
Dr. Michael C. Lorenz's lab at the University of Texas Health Science Center Houston focuses on understanding how a bacterial peptide can inhibit the virulence of human fungal pathogens. Their research is particularly relevant as fungal infections become increasingly resistant to existing treatments. By studying the mechanisms of this peptide, the lab aims to develop new antifungal therapies that could significantly improve health outcomes for patients with serious fungal infections.
fungal infectionsantifungal therapybacterial peptidesvirulence inhibitionextracellular vesicles
Research Aims
3AIM 01Identify characteristics of the bacterial peptide EntV associated with antifungal activity.
AIM 02Develop derivatives of EntV with improved stability and efficacy against fungal infections.
AIM 03Elucidate mechanisms by which EntV inhibits fungal pathogenesis.
Skills the Lab Values
cell cultureanimal modelsbiofilm assaysprotein purificationmolecular cloning
Output against the department
Publications233top 27% of dept.129th of 486
this lab
most publishedleast published
Citations18ktop 22% of dept.106th of 486
this lab
most citedleast cited
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