University of Florida · BiochemistryLi Selenium Lab
Zhipeng Li · Gainesville, Florida
Research Focus
Dr. Zhipeng Li's lab at the University of Florida focuses on understanding the role of the trace element selenium in cellular health. Their research investigates how selenium metabolism affects cell survival and how cells adapt to low selenium levels, which is essential for maintaining redox balance and preventing cell death. By developing a unique low-selenium cell system, the lab aims to uncover mechanisms related to selenium regulation and its implications for diseases related to selenium dysregulation.
selenium metabolismcell viabilityferroptosisredox homeostasisselenoproteinscell stress responselipid peroxidesdisease mechanismsmicronutrients
Research Aims
5AIM 01Investigate how selenium metabolism impacts cell viability.
AIM 02Explore cellular responses to low selenium levels.
AIM 03Identify the mechanisms that regulate selenium metabolism.
AIM 04Develop therapeutic tools for diseases related to selenium dysregulation.
AIM 05Understand the role of selenoproteins in maintaining cellular homeostasis.
Skills the Lab Values
cell culturesynthetic lethal screeninggene expression analysisproteomicsbioinformaticsoxidative stress assayslipid analysisWestern blottingtranscriptomics
Output against the department
Publications68bottom 13% of dept.350th of 402
this lab
most publishedleast published
Citations5.3kbottom 31% of dept.277th of 402
this lab
most citedleast cited
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