University of California-San Francisco · NeuroscienceKramer Cerebrovascular Lab
Joel H Kramer · San Francisco, California
Research Focus
Dr. Joel H. Kramer and his lab at UCSF focus on understanding small vessel cerebrovascular disease, particularly how it contributes to cognitive decline in older adults. They aim to identify reliable markers that can help detect and monitor this disease early on, improving how we diagnose and treat affected patients. By following a diverse group of older individuals showing signs of cerebrovascular issues, they are working to validate new neuroimaging and fluid-based biomarkers that could greatly enhance clinical trials and patient care.
cerebrovascular diseasebiomarkerscognitive declineneuroimagingAlzheimer's diseaseolder adultsclinical trialsblood vesselsearly detectionfunctional decline
Research Aims
5AIM 01Validate novel neuroimaging biomarkers for cerebrovascular disease.
AIM 02Assess blood-based biomarkers in relation to cognitive function.
AIM 03Investigate interactions between cerebrovascular disease and Alzheimer's pathology.
AIM 04Monitor a diverse cohort of older adults over time.
AIM 05Enhance early detection and prognosis methods for cerebrovascular issues.
Skills the Lab Values
MRI imagingbiomarker analysislongitudinal studiespatient enrollmentdata managementcognitive assessmentsresearch collaborationclinical trial designfluid sample processingstatistical modeling
Output against the department
Publications898top 5% of dept.32nd of 671
this lab
most publishedleast published
Citations57ktop 6% of dept.37th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.