Michigan State University · PhysiologyThe Microbiota Nexus Lab
Xianshuang Liu · East Lansing, Michigan
Research Focus
Dr. Xianshuang Liu's lab focuses on understanding how gut bacteria communication influences diabetic peripheral neuropathy, a serious complication of diabetes. The lab studies small particles called extracellular vesicles, which carry signals between cells and can affect inflammation and nerve health. Their research could lead to new treatments for patients suffering from this painful condition.
diabetic peripheral neuropathyextracellular vesiclesgut microbiotaLactobacillusneuropathy therapy
Research Aims
4AIM 01Investigate the role of gut bacterial extracellular vesicles in diabetic peripheral neuropathy.
AIM 02Examine the therapeutic effects of Lactobacillus-derived extracellular vesicles.
AIM 03Explore the molecular mechanisms underlying gut-bacterial communication and nerve damage.
AIM 04Assess the impact of gut dysbiosis on diabetic complications.
Skills the Lab Values
RNA sequencingcell culturediabetic mouse modelsimmunology techniquesin vitro assays
Output against the department
Publications60bottom 10% of dept.256th of 286
this lab
most publishedleast published
Citations2.4kbottom 17% of dept.236th of 286
this lab
most citedleast cited
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