University of California-Davis · Microbiology & ImmunologyEpigenetic Regulation in Germline Development Lab
Satoshi Namekawa · Davis, California
Research Focus
Dr. Satoshi Namekawa's research focuses on understanding how epigenetic mechanisms control the development of sperm and eggs, which are crucial for reproduction. The lab investigates complex processes like spermatogenesis and oogenesis to uncover how these processes ensure the continuity of life from one generation to the next. Their findings hope to enhance our knowledge of germline biology and contribute to advancements in reproductive health.
epigeneticsspermatogenesisoogenesisgermlinesexual dimorphismgene regulationreproductive healthDNA damage responsemeiosisepigenomic reprogramming
Research Aims
5AIM 01Investigate the global epigenetic mechanisms that govern spermatogenesis.
AIM 02Determine the molecular functions of DNA damage response pathways in male germ cells.
AIM 03Analyze the epigenetic processes underlying oogenesis in female germ cells.
AIM 04Explore how distinct features of spermatogenesis and oogenesis intersect.
AIM 05Reveal unifying principles critical for genome maintenance across generations.
Skills the Lab Values
cell cultureWestern blotRNA sequencinggenome editingmicroscopyflow cytometryPCRanimal modelsbioinformaticsdata analysis
Output against the department
Publications132top 49% of dept.236th of 486
this lab
most publishedleast published
Citations4.9kbottom 37% of dept.305th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.