University of Minnesota-Twin Cities · PharmacologyLevinson Drug Discovery Lab
Nicholas Mark Levinson · Minneapolis, Minnesota
Research Focus
Dr. Nicholas Levinson's lab at the University of Minnesota focuses on developing innovative drug discovery technologies, specifically for creating new cancer therapies. The lab is working on a cutting-edge platform that identifies allosteric kinase inhibitors, which can help overcome resistance to current treatments. Their research aims to provide novel therapeutic strategies for cancer patients, particularly targeting proteins involved in tumor growth.
allosteric kinase inhibitorscancer therapeuticshigh-throughput screeningbiophysicsdrug discovery
Research Aims
5AIM 01Develop a high-throughput screening platform for identifying allosteric kinase inhibitors.
AIM 02Target c-Myc through the discovery of Aurora A inhibitors for cancer treatment.
AIM 03Create inhibitors for the c-MET receptor to combat resistance in lung cancer therapies.
AIM 04Translate biophysics research into practical drug development applications.
AIM 05Catalyze the adoption of innovative drug discovery technologies in the pharmaceutical industry.
Skills the Lab Values
high-throughput screening (HTS)fluorescence resonance energy transfer (FRET)nanosecond fluorescence lifetime detectioncell culture techniquesprotein purificationmolecular dockingbioinformatics analysisdata interpretationexperimental designlaboratory safety
Output against the department
Publications49bottom 6% of dept.432nd of 462
this lab
most publishedleast published
Citations1.9kbottom 12% of dept.408th of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.