University of Houston · PharmacologyThe Resistance Solutions Lab
Vincent H Tam · Houston, Texas
Research Focus
Dr. Vincent H Tam's lab focuses on fighting multidrug-resistant bacteria that no longer respond to standard antibiotics. The lab is developing a precision medicine platform that can select effective combinations of antibiotics tailored to individual patients. This research is crucial as it aims to prevent a return to the pre-antibiotic era by finding new ways to use existing drugs more effectively.
multidrug resistanceantibiotic combinationsprecision medicinePseudomonas aeruginosaKlebsiella pneumoniae
Research Aims
4AIM 01Identify effective antibiotic combinations against multidrug-resistant bacteria.
AIM 02Validate predictions from a mathematical model with clinical outcomes.
AIM 03Develop a monitoring device to guide treatment selection.
AIM 04Design a precision medicine platform for antimicrobial therapy.
Skills the Lab Values
data modelingin vitro assaysclinical data analysisantibiotic susceptibility testingmathematical modeling
Output against the department
Publications259top 31% of dept.144th of 462
this lab
most publishedleast published
Citations12ktop 34% of dept.157th of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.