Wichita State University · BiologyBousfield Fertility Lab
George R Bousfield · Wichita, Kansas
Research Focus
Dr. George R. Bousfield's lab at Wichita State University focuses on understanding the role of follicle-stimulating hormone (FSH) in fertility and aging, particularly in women. The lab explores how different forms of FSH, which vary by their sugar modifications, can affect reproductive health and bone density. Through advanced genetic models and cutting-edge techniques, the research aims to provide insights that could lead to better infertility treatments and strategies to combat age-related health issues.
FSHfertilityagingglycoformsmouse modelshormonal signalingreceptor interactionscryogenic electron microscopygranulosa cellstransgenic models
Research Aims
4AIM 01Investigate the impact of FSH glycoforms on fertility in women.
AIM 02Characterize the signaling pathways activated by different FSH forms in ovarian cells.
AIM 03Analyze the internalization and dynamics of the FSH receptor during activation.
AIM 04Explore the structural interactions between FSH and its receptor using advanced imaging techniques.
Skills the Lab Values
PCRcell culturemouse modelsRNA sequencingcryogenic electron microscopyWestern blottingflow cytometrygenetic engineeringbioinformaticsprotein purification
Output against the department
Publications118bottom 42% of dept.591st of 1,033
this lab
most publishedleast published
Citations2.5kbottom 18% of dept.845th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.