Brown University · BiologyIron and Manganese Homeostasis Lab
Thomas Benedict Bartnikas · Providence, Rhode Island
Research Focus
Dr. Thomas Benedict Bartnikas's lab at Brown University focuses on understanding how the body balances iron and manganese levels, which are necessary for health but can be toxic in excess. The lab investigates how inherited conditions, such as hereditary hemochromatosis, affect the regulation and absorption of these metals. Their research helps to uncover the fundamental processes that maintain the balance of important nutrients while preventing toxicity.
iron homeostasismanganese homeostasishereditary hemochromatosisnutrient absorptionmetallomics
Research Aims
3AIM 01Identify the roles of specific transport proteins in manganese homeostasis.
AIM 02Investigate how iron deficiency affects manganese absorption.
AIM 03Determine the impact of manganese excess on disease severity in iron overload conditions.
Skills the Lab Values
mouse modelsmolecular biology techniquesbiochemical assayscell culturegenetic mutagenesis
Output against the department
Publications60bottom 15% of dept.871st of 1,033
this lab
most publishedleast published
Citations3.2kbottom 24% of dept.782nd of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.