Tulane University of Louisiana · BiologyGut-Liver Interaction Lab
Wenke Feng · New Orleans, Louisiana
Research Focus
Dr. Wenke Feng's lab at Tulane University focuses on understanding how gut-derived substances, especially from probiotics, influence liver health in the context of alcohol-associated liver diseases. The research explores the role of specific molecules in regulating bile acid and lipid synthesis, aiming to find new therapeutic strategies for better managing liver diseases associated with alcohol consumption.
Alcoholic Liver DiseaseProbioticsGut MicrobiomeBile AcidsMicroRNALiver HealthTherapeutic StrategyNutritional BiochemistryNanoparticlesMetabolic Syndrome
Research Aims
4AIM 01Determine the role of intestinal miR194 in alcohol-induced liver dysregulation.
AIM 02Investigate how Lactobacillus rhamnosus-derived nanoparticles affect miR194-FXR-FGF15 signaling in ALD.
AIM 03Examine if LDNP treatment alters gut microbiota and bile acid profiles in relation to FXR activation.
AIM 04Evaluate miR194 and FXR activity in human alcohol hepatitis patients.
Skills the Lab Values
Cell CultureAnimal ModelsMolecular CloningRNA ExtractionPCRWestern BlottingMicroscopyBioinformaticsData AnalysisFlow Cytometry
Output against the department
Publications209top 31% of dept.321st of 1,033
this lab
most publishedleast published
Citations9.1ktop 42% of dept.431st of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.