Yale University · BiologyReinisch Lab
Karin M Reinisch · New Haven, Connecticut
Research Focus
Dr. Karin M. Reinisch's lab at Yale University focuses on the molecular mechanisms behind how cells maintain and expand their membrane structures. The research emphasizes understanding how proteins facilitate the transfer of lipids between cellular organelles, a critical process for both cell function and the formation of new organelles, which has implications for understanding neurodegenerative diseases like Alzheimer's and Parkinson's.
lipid transfermembrane dynamicseukaryotic cellsorganelle biogenesisprotein-mediated transportneurodegenerative diseasesendoplasmic reticulummembrane contact sitesautophagosome formation
Research Aims
5AIM 01Identify proteins at membrane contact sites
AIM 02Elucidate lipid transfer processes
AIM 03Characterize lipid transfer proteins that bridge organelles
AIM 04Investigate the role of proteins in organelle biogenesis
AIM 05Explore connections between lipid transfer and neurological disorders
Skills the Lab Values
cell cultureprotein characterizationlipid biochemistrymicroscopy techniquesWestern blotRNA sequencingcryo-electron microscopygenetic manipulation in yeastbiochemical assays
Output against the department
Publications149top 46% of dept.470th of 1,033
this lab
most publishedleast published
Citations9.6ktop 40% of dept.410th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.