University of California-San Francisco · Microbiology & ImmunologyEnterovirus Pathogenesis Lab
Raul Andino · San Francisco, California
Research Focus
Dr. Raul Andino's lab at UCSF focuses on understanding how enteroviruses, which can cause severe illnesses in children, infect cells and tissues. The research utilizes advanced techniques in genomics and single-cell analysis to explore how these viruses replicate and how the body responds to them. The ultimate aim is to improve our understanding of the pathogenesis of these infections, leading to the development of better vaccines and antiviral therapies.
enterovirusviral pathogenesissingle-cell genomicstissue tropismhost immune response
Research Aims
5AIM 01Map how enteroviruses infect different cell types during infection.
AIM 02Profile the host's immune response using single-cell transcriptomics.
AIM 03Analyze viral mutations in various tissues during the infection process.
AIM 04Investigate the impact of interferon diversity on enterovirus infections.
AIM 05Develop strategies for effective antiviral drugs and vaccines.
Skills the Lab Values
single-cell RNA sequencingultra-deep sequencingmouse modelsCRISPR/Cas9data analysiscell cultureviral culturebioinformaticsflow cytometry
Output against the department
Publications252top 22% of dept.106th of 486
this lab
most publishedleast published
Citations24ktop 14% of dept.69th of 486
this lab
most citedleast cited
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