University of Virginia-Main Campus · PhysiologyAi Imaging Lab
Huiwang Ai · Charlottesville, Virginia
Research Focus
Dr. Huiwang Ai's lab at the University of Virginia focuses on developing advanced imaging techniques to study neurological disorders like Alzheimer's disease. The lab creates genetically encoded fluorescent indicators to visualize oxidative stress and synaptic zinc dynamics in real-time within brain tissues. This research aims to improve our understanding of the mechanisms underlying these disorders, potentially leading to new therapeutic approaches.
Alzheimer's DiseaseOxidative StressGenetically Encoded IndicatorsNeuromodulatorsZinc Dynamics
Research Aims
5AIM 01Develop fluorescent redox indicators to assess oxidative stress in Alzheimer's models.
AIM 02Optimize genetically encoded indicators for imaging synaptic zinc in the brain.
AIM 03Evaluate oxidative stress during disease progression and therapy in animal models.
AIM 04Investigate the role of synaptic zinc in auditory processing.
AIM 05Create tools to enhance imaging capabilities for other genetically encoded indicators.
Skills the Lab Values
Fluorescence ImagingGenetic EngineeringAnimal ModelsCell CultureBehavioral TestingMolecular Biology TechniquesData Analysis in ImagingMicroscopy
Output against the department
Publications105bottom 31% of dept.197th of 286
this lab
most publishedleast published
Citations4.7kbottom 39% of dept.173rd of 286
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.