Columbia University in the City of New York · NeuroscienceVilas Menon Lab
Vilas Menon · New York, New York
Research Focus
Dr. Vilas Menon's lab at Columbia University focuses on understanding the complex interactions between different cell types involved in Alzheimer's Disease (AD). By using induced pluripotent stem cells (iPSCs) from donors with varying AD pathology, the lab aims to explore how these cells communicate and influence each other in the progression of cognitive decline. This research is critical for identifying potential clinical targets for Alzheimer's intervention.
Alzheimer's Diseasecell interactionsiPSC technologycognitive declineneurodegenerationproteomicstranscriptomicsdisease modeling
Research Aims
5AIM 01Investigate cell type-specific changes associated with Alzheimer's Disease.
AIM 02Analyze interactions between neurons, astrocytes, and microglia in AD pathology.
AIM 03Use iPSCs to model Alzheimer's disease and identify genetic risk factors.
AIM 04Evaluate the effects of AD-related genetic backgrounds on cell behavior in vitro.
AIM 05Prioritize biological pathways for potential therapeutic intervention in Alzheimer's Disease.
Skills the Lab Values
cell cultureinduced pluripotent stem cell (iPSC) techniquesco-culture techniquessingle-cell RNA sequencingmolecular profilingproteomics analysisgenome-wide association studies (GWAS)data analysis using bioinformatics software
Output against the department
Publications307top 21% of dept.144th of 671
this lab
most publishedleast published
Citations15ktop 27% of dept.178th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.