Clemson University · Biomedical EngineeringVyavahare Lab
Naren R Vyavahare · Clemson, South Carolina
Research Focus
Dr. Naren Vyavahare's lab at Clemson University focuses on developing innovative therapies for aortic aneurysms, a serious cardiovascular condition. The research involves using nanoparticle systems to target and repair damaged vascular elastin, which is crucial for preventing aneurysm ruptures. By applying these therapies in preclinical models, the lab aims to create a non-invasive treatment that could change how these dangerous conditions are managed, potentially saving lives and improving patient outcomes.
aortic aneurysmsnanoparticle therapyvascular elastinconnective tissue disorderscardiovascular health
Research Aims
3AIM 01Develop a nanoparticle delivery system targeting degraded vascular elastin.
AIM 02Test the effectiveness of elastin-targeting nanoparticles in animal models of Marfan syndrome.
AIM 03Evaluate the impact of DESTINeD therapy on the growth reversal of aortic aneurysms.
Skills the Lab Values
nanoparticle designmouse modelsswine modelsintravital microscopydrug delivery systems
Output against the department
Publications76bottom 11% of dept.528th of 595
this lab
most publishedleast published
Citations2.6kbottom 19% of dept.481st of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.