Northwestern University · BiologyFang Lab
Deyu Fang · Evanston, Illinois
Research Focus
Deyu Fang's research lab focuses on developing innovative treatments for triple negative breast cancer by combining immunotherapy and chemotherapy. The lab's goal is to create therapies that not only target cancer cells but also enhance the immune system's ability to fight tumors, particularly those that are resistant to existing treatments. They explore the role of specific proteins, like USP22, in cancer cell growth and immune response to devise effective therapeutic strategies.
triple negative breast cancerimmunotherapychemotherapycancer stem cellsUSP22antitumor therapysolid tumorsimmune checkpoint inhibitorssmall molecule inhibitors
Research Aims
4AIM 01Develop a novel treatment targeting triple negative breast cancer using dual immuno- and onco-targeting strategies.
AIM 02Investigate the role of USP22 in tumor progression and immune evasion.
AIM 03Enhance the efficacy of cancer therapies by minimizing immune-related toxicities.
AIM 04Target cancer stem cells to prevent recurrence and metastasis.
Skills the Lab Values
cell culturemouse modelsflow cytometryWestern blotRNA sequencingdrug kineticsclinical trial designmolecular biology techniquesimmunologic assays
Output against the department
Publications281top 21% of dept.216th of 1,033
this lab
most publishedleast published
Citations13ktop 29% of dept.297th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.