Stanford University · BiologyBladder Pain Research Unit
Philip A Beachy · Stanford, California
Research Focus
Philip A Beachy's lab at Stanford University focuses on understanding and treating Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS), a painful condition that disrupts the lives of millions, particularly women. By exploring the regulation of bladder sensory nerves and the integrity of the bladder lining, the lab aims to identify new therapeutic strategies that could replace opioid treatments, thereby reducing addiction risks. Their research utilizes a combination of advanced genetic techniques and cellular analysis to uncover the complex mechanisms behind this condition.
Interstitial CystitisBladder Pain Syndromeurothelial integritysensory nerve-associated mesenchymesingle cell RNA sequencingopioid addictionneurotrophinsanimal modelsneuropeptide signalingpain management
Research Aims
3AIM 01Investigate signal pathways involved in the production of neurotrophins by specialized bladder mesenchyme.
AIM 02Characterize the interaction between sensory neurons and the urothelium in bladder function.
AIM 03Evaluate pharmacologic agents in animal models to modulate signaling and assess their potential as treatments for IC/BPS.
Skills the Lab Values
single cell RNA sequencingmouse modelspharmacologic interventioncell cultureneuroanatomical tracingmolecular biology techniquesbioinformaticsimmunohistochemistrytissue biopsy techniques
Output against the department
Publications190top 34% of dept.349th of 1,033
this lab
most publishedleast published
Citations47ktop 6% of dept.59th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.