University of Florida · BiologyProkop Lab
Stefan Prokop · Gainesville, Florida
Research Focus
Dr. Stefan Prokop's lab at the University of Florida focuses on understanding how certain proteins in the brain contribute to Alzheimer's disease (AD). They are investigating the role of amyloid-associated proteins (AAPs) in the progression of the disease, particularly how these proteins might affect neurodegeneration over time. By studying these processes, the lab aims to identify potential new therapeutic targets to combat AD and improve patient outcomes.
Alzheimer's Diseaseamyloidneurodegenerationproteomicstherapeutic targets
Research Aims
3AIM 01Evaluate the accumulation patterns of amyloid-associated proteins in Alzheimer's disease and animal models.
AIM 02Assess how the expression of AAPs alters amyloid deposition and other aspects of AD pathology.
AIM 03Investigate the mechanisms by which AAPs interact with amyloid plaques and influence their properties.
Skills the Lab Values
mouse modelsproteomicsAAV-mediated gene deliveryimmunohistochemistrydata analysiscell signaling pathwaysWestern blottingbiomarker identification
Output against the department
Publications123bottom 44% of dept.575th of 1,033
this lab
most publishedleast published
Citations6.6kbottom 47% of dept.551st of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.