Oklahoma State University-Main Campus · PsychologyChannappanavar Lab
Rudragouda Channappanavar · Stillwater, Oklahoma
Research Focus
Dr. Rudragouda Channappanavar's research lab at Oklahoma State University focuses on understanding how respiratory viruses, particularly SARS-CoV-2, cause severe lung problems and disrupt the immune response. The lab investigates the signaling pathways involved in inflammation and how blocking these pathways might improve treatments for viral infections. Overall, their work aims to find new ways to enhance the immune response and reduce lung damage caused by infections.
SARS-CoV-2immunologylung pathologyERK1/2 signalingviral infectionsinflammationacute lung injury
Research Aims
5AIM 01Investigate the role of TLR-ERK1/2 signaling in SARS-CoV-2-induced lung injury.
AIM 02Evaluate the impact of myeloid cell-intrinsic signaling on immune response during infections.
AIM 03Test the therapeutic potential of inhibiting ERK1/2 to reduce lung inflammation.
AIM 04Explore the relationship between excessive inflammation and severe pneumonia in viral infections.
AIM 05Identify potential treatment strategies to enhance antiviral immunity and minimize lung damage.
Skills the Lab Values
cell cultureanimal modelscytokine assaysPCRflow cytometryin vivo imagingWestern blotdata analysis with R/Pythonviral load measurementimmunofluorescence microscopy
Output against the department
Publications72bottom 17% of dept.246th of 296
this lab
most publishedleast published
Citations10ktop 28% of dept.82nd of 296
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.