University of Missouri-Columbia · EngineeringAstrocyte Recovery Lab
Shinghua Ding · Columbia, Missouri
Research Focus
Dr. Shinghua Ding's lab investigates how brain cells called reactive astrocytes change their metabolism after a stroke, particularly focal cerebral ischemia (FCI). By understanding these changes, the lab aims to discover new ways to promote brain repair and improve recovery in stroke patients. Their work combines animal models and advanced techniques to analyze brain function and metabolism, which could lead to better treatments for stroke-related injuries.
strokereactive astrocytesmetabolic reprogrammingfocal cerebral ischemiabrain repair
Research Aims
3AIM 01Characterize the metabolic phenotype of reactive astrocytes after focal cerebral ischemia.
AIM 02Investigate how HIF1 regulates the production of NAMPT in reactive astrocytes.
AIM 03Study the mechanisms by which reactive astrocytes aid in brain repair after stroke.
Skills the Lab Values
metabolomic analysismouse modelsRNA sequencingtwo-photon imagingcell culture
Output against the department
Publications64bottom 10% of dept.249th of 278
this lab
most publishedleast published
Citations3.0kbottom 23% of dept.215th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.