EUEmory University · Microbiology & Immunology
Streptococcus Infections and Cell Death Unit
Christopher N Larock · Atlanta, Georgia
Research Focus
Dr. Christopher N. Larock's research lab at Emory University focuses on understanding how the bacteria Streptococcus pyogenes causes severe infections and illness. The lab studies the interactions between this bacterium and skin cells, specifically looking at a novel cell death process that could reveal new ways to treat serious infections. By examining these cellular processes, the lab aims to identify potential therapeutic targets that could improve patient outcomes for diseases caused by this pathogen.
Streptococcus pyogenescell deathpyroptosiskeratinocytesinfectionimmune defensenecrotizing fasciitisrheumatic heart disease
Research Aims
4AIM 01Investigate how Streptococcus pyogenes induces cell death in skin cells.
AIM 02Examine the role of gasdermin A in the immune response to infection.
AIM 03Identify the impact of cell death on bacterial survival and infection progression.
AIM 04Explore therapeutic targets based on understanding of bacterial manipulation of host cells.
Skills the Lab Values
cell culturemolecular biology techniquesanimal modelsin vitro infection modelsprotein analysisimmunohistochemistrybiochemical assaysmicroscopy
Output against the department
Publications52bottom 12% of dept.427th of 486
this lab
most publishedleast published
Citations2.0kbottom 13% of dept.424th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.