University of Chicago · ChemistryVoth Lab
Gregory A. Voth · Chicago, Illinois
Research Focus
Dr. Gregory A. Voth's lab focuses on using advanced computer simulations to better understand complex biological processes, specifically related to HIV-1 and cellular mechanics. By modeling how proteins interact with cell membranes and each other, the lab aims to uncover vital steps in the life cycle of the HIV virus and the mechanisms that allow cells to move and interact. This research has implications for developing new treatments for diseases related to HIV and cellular dysfunction.
HIV-1molecular dynamicsbiomolecular processescell membranesprotein interactionsmultiscale simulationcytoskeletonvirion maturationcellular motilitymembrane remodeling
Research Aims
5AIM 01Simulate the release and maturation of HIV-1 virions to understand viral lifecycle processes.
AIM 02Investigate protein-protein interactions that influence cellular membrane mechanics.
AIM 03Model the reorganization of proteins during the assembly of viral capsids.
AIM 04Explore the dynamics of cellular structures like filopodia and lamellipodia during cell movement.
AIM 05Develop computational methods to predict the behavior of biomolecular processes at multiple scales.
Skills the Lab Values
molecular dynamics simulationcoarse-grained modelingprotein-protein interaction studiescell membrane simulationcomputer-aided drug designdata analysis in Pythonmembrane dynamics modelinghigh-performance computingtheoretical biophysicscollaborative experimental methods
Output against the department
Publications990top 4% of dept.9th of 216
this lab
most publishedleast published
Citations58ktop 6% of dept.12th of 216
this lab
most citedleast cited
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