Harvard University · BiochemistrySulfate Solutions Lab
Abigail Sloan Devlin · Cambridge, Massachusetts
Research Focus
Dr. Abigail Sloan Devlin's lab at Harvard Medical School focuses on understanding the role of microbiome-derived sulfated metabolites in human health. Their research investigates how these compounds, produced by gut bacteria, can influence immune responses and potentially lead to new therapies for diseases like autoimmune disorders. By combining analytical chemistry and biological studies, the lab aims to uncover the identity and function of these metabolites and the bacteria that produce them.
microbiomesulfated metabolitesimmune responseautoimmune diseasesanalytical chemistrymetabolomicsgut bacteriaprobioticsinflammatory diseases
Research Aims
4AIM 01Identify microbiome-derived sulfated metabolites using advanced analytical techniques.
AIM 02Characterize the bacteria responsible for producing these sulfated compounds.
AIM 03Investigate the immunological effects of sulfated metabolites on T cells in vitro and in vivo.
AIM 04Explore the potential of probiotics and small molecules for treating autoimmune diseases.
Skills the Lab Values
PCRmouse modelscell culturecomparative metabolomicsbioinformaticsanalytical chemistrymicrobial culturinggene expression analysisbiochemical assays
Output against the department
Publications43bottom 6% of dept.379th of 402
this lab
most publishedleast published
Citations15ktop 32% of dept.129th of 402
this lab
most citedleast cited
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