Washington University in St Louis · BiochemistryGreenberg Cardiomyopathy Lab
Michael J Greenberg · Saint Louis, Missouri
Research Focus
Dr. Michael J Greenberg's lab focuses on understanding the genetic causes of heart diseases, specifically cardiomyopathies, which can lead to heart failure. The team aims to develop new, more effective treatments by using a precision medicine approach that considers the unique genetic makeup of individual patients. They integrate various advanced techniques to model mutations and test how these influence heart cell and tissue function, paving the way for tailored therapies for patients with specific genetic mutations.
cardiomyopathyprecision medicinegenotype-phenotypemolecular dysfunctionsmall molecule therapeutics
Research Aims
4AIM 01Investigate the link between genetic mutations and heart muscle dysfunction.
AIM 02Identify subgroups of patients with common molecular dysfunctions in cardiomyopathies.
AIM 03Develop compounds that can reverse the molecular dysfunction caused by specific mutations.
AIM 04Evaluate how restoring molecular function can improve heart cell and tissue health.
Skills the Lab Values
biochemical techniquescell culturetissue engineeringbiophysical analysisgenetic modeling
Output against the department
Publications258top 28% of dept.112th of 402
this lab
most publishedleast published
Citations8.5kbottom 45% of dept.221st of 402
this lab
most citedleast cited
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