Drexel University · PharmacologyHIV Drug Interaction Research Lab
Jacqueline M Barker · Philadelphia, Pennsylvania
Research Focus
Dr. Jacqueline M Barker's lab focuses on understanding how drug use, specifically cocaine exposure, interacts with HIV treatments and hormonal regulation. They explore the behavioral and hormonal impacts of antiretroviral therapy and its effects on the neuroimmune system, aiming to develop strategies to reduce drug cravings and improve treatment outcomes for individuals living with HIV. The research has potential implications for preventing HIV transmission and aiding those struggling with substance use disorders.
antiretroviralscocaineHIVhormonal regulationdrug cravingneuroimmune systemrelapse preventionprogesteroneEcoHIV model
Research Aims
3AIM 01Assess how PrEP and ART impact estrous cyclicity and neuroimmune signaling after cocaine exposure.
AIM 02Determine the role of mPOA neuronal and astrocytic populations in cocaine reinstatement following HIV treatment.
AIM 03Evaluate the effects of allopregnanolone on drug craving behavior and immune responses.
Skills the Lab Values
animal modelshormonal assaysin vivo imagingchemogeneticsbehavioral testingcell cultureflow cytometryPCRWestern blotdata analysis
Output against the department
Publications78bottom 17% of dept.381st of 462
this lab
most publishedleast published
Citations1.7kbottom 11% of dept.413th of 462
this lab
most citedleast cited
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